This release features preliminary support for Varnish using the Turpentine module for Magento. The change should not affect current Hypernodes, because Varnish is disabled by default (requests are not routed through Varnish, nor is it started by default so it does not use up any memory). Customer overrides of Nginx should all still work.
To enable Varnish, we will launch a Service Panel button that toggles Varnish. This interface is currently still undergoing testing. If you are interested, please let us know.